Compute the RaCInG kernel for one or more patients
Usage
compute_kernel(liglist, reclist, Cmatrix, LRmatrix, normalize = FALSE)
Arguments
- liglist
Cell-by-ligand compatibility matrix.
- reclist
Cell-by-receptor compatibility matrix.
- Cmatrix
Patient-by-cell-type abundance matrix.
- LRmatrix
Ligand-by-receptor-by-patient interaction tensor.
- normalize
Logical; if TRUE, also compute a uniformized baseline kernel.
Value
Either a 3D kernel array or a list with kernel and kernel_norm.
