Remove low variance deconvolution features

Removes features that barely vary across samples: features whose coefficient of variation (CV = standard deviation / mean) is below cv_thr. Each feature is judged on its own, so features of rare cell types (small values) are kept as long as they vary relative to their size.

Usage

remove_low_variance(data, cv_thr = 0.1)

Arguments

data

Deconvolution features

cv_thr

Minimum coefficient of variation; features below it are discarded.

Value

A list containing

• Deconvolution matrix after removal of low variance.

• Discarded low variance features.