Compute deconvolution subgroups — compute_subgroups • multideconv

Compute deconvolution subgroups

Usage

compute_subgroups(
  deconvolution,
  thres_corr,
  corr_type,
  file_name,
  batch = NULL
)

Arguments

deconvolution: A matrix with unprocessed cell deconvolution results
thres_corr: A numeric value with the minimum correlation allowed to group cell deconvolution features
corr_type: Correlation type whether "spearman" or "pearson".
file_name: Base name for subgroup
batch: Optional batch covariate used to compute partial correlations.

Value

A list containing

A matrix with the processed deconvolution features
Cell subgroups obtained by linear correlation
Cell subgroups obtained by proportionality correlation
Discard cell features either because of low variance or high zero number