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Run Wilcoxon tests across network features

Source: R/statistical_analysis.R
wilcox_group_test.Rd

Runs a Wilcoxon rank-sum test per feature (column) between every pair of groups. Also reports the fold change (ratio of group means) so results can be plotted with top_features_plot().

Usage

wilcox_group_test(data_matrix, groups, p_adjust_method = "fdr")

Arguments

data_matrix

Numeric matrix or data frame with patients in rows and features in columns.

groups

Vector of group labels with length matching nrow(data_matrix). When more than two groups are present, every pairwise comparison is run.

p_adjust_method

Multiple-testing correction method passed to stats::p.adjust().

Value

A data frame with one row per feature per group comparison, including Comparison, Wilcox_statistic, Fold_change, Log2FC, P_value, and Adjusted_P_value (adjusted jointly across all comparisons).