Compute a cell-type composition matrix from deconvolution subgroups

Builds a binary presence matrix indicating which original cell types are present in higher-level cell groups.

Usage

# S3 method for class 'composition.matrix'
compute(deconvolution.subgroupped, cell.groups, cells_extra = NULL)

Arguments

deconvolution.subgroupped

A list containing "Deconvolution subgroups composition" per model.

cell.groups

A list containing cell group definitions, where the second element holds the groupings.

cells_extra

Optional vector of additional cell identifiers to consider during extraction.

Value

A binary matrix (data.frame) where rows are cell groups and columns are cell types (1 = present, 0 = absent).